Jason Smith

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WORK HISTORY

ACADEMIC AND RESEARCH EXPERIENCE

Senior Scientist - Bioinformatician, Department of Pediatrics University of Virginia, Charlottesville, VA
[06/2022 –]

  • Design and implement tools for epigenetic analysis of the transcriptome and accessibilome
  • Design experiments to investigate renal cell biology
  • Analyze multiomics data related to kidney development and disease

PhD Student/Candidate, Department of Biochemistry & Molecular Genetics University of Virginia, Charlottesville, VA
[06/2017 – 06/2022]

  • Developed Python and R based pipelines for nascent RNA sequencing and ATAC-seq analysis
  • Developed algorithms for region based annotation and clustering
  • Developed bioinformatic infrastructure to aid genome analyses
  • Integrated single-cell RNA-seq and ATAC-seq to study renin cell biology

Lab Specialist I, Department of Pharmacology
University of Virginia, Charlottesville, VA
[08/2015 – 06/2017]

  • Design and implement independent experiments to further laboratory research goals
  • Assist collaborators in the statistical analysis of experimental results
  • Manage and facilitate undergraduate and graduate student researchers in independent projects
  • Oversee general laboratory management practices and inventory

Bioinformatician I, Institute for Genome Sciences and Policy
Duke University Medical Center, Durham, NC
[09/2009 – 09/2010]

  • Implemented the Illumina Genome Analyzer pipeline (a Linux based command driven sequence analysis software package) and analyzed human whole genome and exome data
  • Programmed and implemented Bash shell-scripts and C++ for human and mouse sequence analysis
  • Oversaw operation and maintenance of thirteen Illumina Genome Analyzer II instruments and two Illumina HiSeq 2000 instruments, while supervising four employees

Research Technician II, Institute for Genome Sciences and Policy
Duke University Medical Center, Durham, NC
[10/2005 – 09/2009]

  • Designed, adapted and implemented protocols for sequencing, genotyping and expression studies
  • Performed and analyzed PCR, Sanger sequencing, TaqMan, Illumina Goldengate/BeadXpress, and Illumina Infinium assays
  • Managed laboratory employees and interactions with other labs

TEACHING EXPERIENCE

Graduate Assistant – Health and Human Performance, College of Charleston
Silcox Gym, Charleston, SC [01/2014 – 05-2014]

  • Graded and prepared assignments, quizzes, and exams for Exercise Science professors
  • Prepared and maintained Health and Human Performance news and reports
  • Performed campus assignments for Health and Human Performance department

Teaching Assistant – Introduction to Cell and Molecular Biology, College of Charleston
Rita Liddy Hollings Science Center, Charleston, SC
[08/2013 – 12/2013]

  • Instructed 20 – 30 students on proper laboratory techniques and methodology
  • Maintained and prepared reagents and laboratory space for students
  • Graded in-class assignments and quizzes

Teaching Assistant – Molecular Biology Lab, College of Charleston
Rita Liddy Hollings Science Center, Charleston, SC
[08/2012 – 05/2013]

  • Led 15 – 25 upper level undergraduates in performing individual research projects, and graded in-class assignments and quizzes
  • Instructed students on proper laboratory techniques and methodology
  • Maintained and prepared reagents and laboratory space for students

Teaching Assistant – Evolution, Form, and Function of Organisms Lab, College of Charleston
Lightsey Center, Charleston, SC
[08/2011 – 12/2011]

  • Instructed 25 – 30 biology and non-biology majors and led students in weekly lab activities/experiments
  • Designed and graded weekly assignments and quizzes